San Francisco mourns mayor and homelessness campaigner Edwin Lee
San Francisco's mayor Edwin Lee has died at the age of 65.
San Francisco Board of Supervisors president London Breed said on Tuesday that Mr Lee died just after 1am at Zuckerberg San Francisco General Hospital.
A statement from the mayor's office said: "It is with profound sadness and terrible grief that we confirm that Mayor Edwin M. Lee passed away on Tuesday ... ."
The statement says family, friends and colleagues were at Mr Lee's side.
Mr Lee was not known to be ill.
No other details have been released.
Mr Lee was appointed as mayor in 2011, replacing mayor Gavin Newsom, who was elected the state's lieutenant governor.
He went on to win the 2011 election and was re-elected in 2015.
He was known for his work against homelessness.
Ms Breed assumes the role of acting San Francisco mayor.