Liverpool's treble dreams came to a shuddering halt as Chelsea added to their recent misery by knocking them out of the FA Cup at Stamford Bridge.
Willian's effort and Ross Barkley's sensational solo strike wrapped up a 2-0 win for Frank Lampard's side, condemning the Reds to their third defeat in four games and ending their hopes of winning the three major trophies this season.
The Blues were good value for their win and deservedly take their place in the draw for the quarter-finals, although they were aided by Adrian's howler as the keeper deflected Willian's tame drive into his own net when he should have made the save.
Jurgen Klopp's men are now left to pick up the pieces from a shocking and unforeseen dip in form, during which they have been knocked out of the FA Cup and lost their unbeaten run in the Premier League in their last four games, and they are still facing the prospect of having to battle from behind in their Champions League last-16 tie with Atletico Madrid.
Elsewhere, Newcastle United eased into the quarter-finals by holding on for a 3-2 win over West Bromwich Albion at The Hawthorns.