Chelsea completely lost their discipline as two red cards, seven yellow cards and a penalty handed QPR a 1-0 win and a first victory over their arch-rivals for 16 years.
Jose Bosingwa and Didier Drogba both saw red in the Barclays Premier League clash at Loftus Road, while Ashley Cole also picked up a suspension for his fifth booking of the season.
The rot set in when David Luiz needlessly conceded an eighth-minute penalty which Heidar Helguson scored.
The visitors continued to boss possession but they were not creating anything of note, and their afternoon took another turn for the worse in the 32nd minute when Bosingwa was controversially sent off.
He hauled down Shaun Wright-Phillips when the winger threatened to burst clear, with Chris Foy deeming the right-back to be last man and brandishing red.
Blues boss Andre Villas-Boas sacrificed Daniel Sturridge for Branislav Ivanovic but his misery was far from over, with Drogba suicidally getting himself sent off four minutes before half-time.
The striker lunged in two footed on Adel Taraabt and - unlike his other two major decisions - left Foy with little option.
Frank Lampard was furious midway through the second half when he felt Fitz Hall had bundled him over in the box, only to see the officials unmoved.
Chelsea should have snatched an equaliser with just over 10 minutes left when Ivanovic put the ball on a plate for sub Nicolas Anelka, who somehow headed the ball straight at Paddy Kenny from four yards.
And Chelsea wasted another great chance to level when Lampard deflected Luiz's overhead kick over the crossbar.