Charlie Adam missed a penalty as Liverpool's disappointing run against Wigan continued with a 0-0 draw at the DW Stadium.
The Scotland international's effort was saved by Ali Al Habsi after Gary Caldwell had handled an overhead kick from Luis Suarez, playing 24 hours after learning he had been given an eight-match ban by the Football Association.
Wigan were well worth their point and probably should have had a penalty of their own in the first half when Martin Skrtel appeared to bring down Victor Moses.
Liverpool have taken three points from their last four matches against them and have not won at Wigan since September 2007.
For the Latics is was a second successive home draw against one of the 'big' teams - having held Chelsea on Saturday, and another point towards their survival battle.
Dirk Kuyt had the best chance from Stewart Downing's cut-back but Al Habsi did enough to turn aside the shot.
For all their dominance the visitors began to lose a grip on the game and could well have gone into half-time behind had referee Michael Oliver deemed Skrtel's challenge inside the area on Moses - in which there appeared to be contact - a foul.
Soon after the restart Al Habsi tipped over a Suarez free-kick but it was the hands of Wigan captain Caldwell which made a more decisive intervention in the 50th minute.
Suarez's attempted overhead kick hit the centre-back on his left arm and Oliver pointed to the spot but Adam's penalty was saved by Al Habsi.
Hugo Rodallega, Wigan's scorer in two of their last three meetings with Liverpool, came on for Conor Sammon and almost came up trumps with a far-post header from Moses' cross which was deflected behind by Glen Johnson.