Saturday's Barclays Premier League matches at Wigan and Liverpool have both fallen foul of the weather, the clubs have confirmed.
Wigan's home match against Aston Villa at the DW Stadium and Liverpool's game against Fulham were both postponed due to heavy overnight snow.
Temperatures were predicted to be -6 degrees at the scheduled 5.30pm kick-off time at Anfield, but conditions around the ground and on roads in the area forced an early postponement.
"Club officials met with the police (on Saturday morning) to assess the prevailing weather conditions," said a Liverpool spokesman.
"The safety of all fans attending the game is paramount and although the Anfield pitch is playable, the conditions around the stadium and further afield for people travelling to the match are such that the decision was taken, following police advice on safety grounds, to postpone the game.
"All existing tickets will remain valid for the re-arranged fixture and supporters will be advised of the new date as soon as possible."
The Latics earlier issued a statement confirming their game had been postponed, citing "freak snow" as the reason.
In the npower Championship, Cardiff's match against Burnley fell foul of the latest big freeze on Friday night following heavy snowfall in south Wales.
The League One games at Rochdale, Walsall, Hartlepool, Leyton Orient, Yeovil, Brentford, Bristol Rovers, MK Dons and Swindon are also off, along with those at Bury, Accrington, Hereford, Cheltenham, Oxford, Aldershot, Port Vale and Crewe in League Two.
In Scotland, Hamilton's home game against Celtic became the fourth casualty in the Clydesdale Bank Premier League after the Rangers-St Mirren, Aberdeen-Motherwell and St Johnstone-Dundee United clashes were postponed on Friday.