Frankie Dettori can bridge an eight-year gap and cane the bookies in the process by winning the Derby on board Golden Horn at Epsom.
And there is strong Ulster interest in the £1.4million showpiece with Banbridge rider Pat Cosgrave taking the reins on Storm The Stars.
But Dettori - whose last ride in the Derby was in 2011 and sole victory in 2007 on Authorized - is the man grabbing most of the limelight.
The Italian famously hammered the bookies with his 'Magnificent Seven' winners right through the card at Ascot in 1996.
Conservative estimates had the bookies crying into their beer to the tune of £30million.
And although a victory in today's Derby wouldn't hurt the bookies to the same degree, it would certainly leave them many millions out of pocket.
William Hill spokesman Jon Ivan-Duke said: "Frankie Dettori is the one jockey who everyone knows, as we have found out to our peril.
"The Derby is the biggest Flat race of the year and if Frankie guides the favourite home, the industry will be paying out tens of millions."
Coral spokesman David Stevens added: "Although his status as the punters' favourite has dipped in recent years, his presence on board this year's Epsom favourite will see him return to centre stage.
"Golden Horn will be the first name on thousands of betting slips and another Derby victory for the Italian star in what is by far the highest turnover race of the Flat season will see the bookies paying out millions."
Dettori said: "I have lots of faith in the horse.
"Let's hope we get a smooth run and see if we can win it," he added.
Golden Horn's trainer John Gosden said: "Hopefully Frankie can deliver him when it matters."
As for Cosgrave, a first ever ride in the Derby represents a huge turnaround in fortunes after breaking his leg in a fall in March.
"How things have changed. You've got to take racing day by day," said the Ulsterman.