Davy Condon has been forced to retire from the saddle due to a spinal injury.
Condon was riding Portrait King in the Grand National at Aintree when he fell at the third-last, leaving him with a spinal concussion.
It was the second time within a year that he suffered a similar injury.
Condon had resigned himself to the fact he would be out of action for a lengthy period of time but after seeing a specialist on Wednesday he has been advised to call time on his career.
Dr Adrian McGoldrick, chief medical officer of the Irish Turf Club issued a statement on behalf of Condon which read: "Davy Condon suffered a spinal injury in a fall during the Grand National at Aintree.
"This was on the background of a previous spinal concussion from which he had recovered fully and had been passed fit to ride by our consultant neurologist.
"Davy was reviewed yesterday by Dr Brian Murray, Consultant Neurologist, on behalf of the Turf Club.
"Dr Murray has recommended that Davy retire from horse riding, be it professional or recreational, due to the risk of further spinal injury.
"Davy has been referred by Dr Murray for a neurosurgical opinion as he has an ongoing disc lesion in his neck.
"Davy has fully accepted the medical advice and will be liaising with the Irish Jockeys' Trust with a view to future career options."
Condon's best days in the saddle in recent years came when riding for Gordon Elliott and the trainer was quick to take to Twitter to pay tribute to him.
"Very sad to say that Davy Condon has been forced to retire from racing due to injury," said Elliott.
"Davy has been an integral part of the team and has ridden some of the biggest winners I have had in my short career.
"Davy will not only be missed by myself, he is a very popular person in the industry and here at Cullentra.
"We all wish him the very best of luck with whatever he chooses to do next with his career and if we can help in any way, we will not hesitate to do so.
"Thanks for everything Davy, we've had some great memories together."
Condon's last major win came at Ascot in The Ladbroke on the Elliott-trained Bayan, which was only his third ride back since the first bad back injury he suffered in August.
His last Grade One success came on Pat Fahy's Morning Assembly at the 2013 Punchestown Festival and he also won a Powers Gold Cup on Realt Mor for Elliott earlier that season.
The early days of his career were spent with Willie Mullins and he first came to prominence to British race fans when winning the 2007 Supreme Novices' Hurdle on Ebaziyan.