Uranna will bid to provide the Supreme Horse Racing Club with their first National Hunt winner on British soil as she crosses the Irish Sea to contest the Weatherbys GSB Jane Seymour Mares' Novices' Hurdle at Sandown on Friday.
The successful syndicate enjoyed Royal Ascot glory when Pique Sous clinched victory in the Queen Alexandra Stakes last summer, but that remains their only winner outside of Ireland.
French recruit Uranna made an encouraging debut for Willie Mullins when third at Limerick in early November and she returned to the Patrickswell circuit to get off the mark over Christmas. She steps up to Listed class for her latest assignment, with Ruby Walsh travelling over for the ride.
Supreme racing manager Steve Massey said: "We always thought a lot of her but she picked up an injury when she came over from France and the owners have had to be very patient, but hopefully it will pay off.
"We were delighted with her at Limerick over Christmas and the second and third have won since, so the form looks good. The better ground should suit her. She won on heavy ground last time, but we definitely think she can improve on better ground.
"It's great to be having a runner at Sandown on a big day and if she can pick up some prize-money and a big of black type, we'll be delighted. We think she's a chaser for next year and anything she does over hurdles will be a bonus, but we're hopeful."
Uranna features in an 11-runner field, with the Peter Bowen-trained Rons Dream the highest rated mare in the line-up.
Nicky Henderson runs Broxbourne and Heltara, while the Alan King-trained Gabriella Rose and Madame Trigger from Dan Skelton's yard are also in contention.
Jonjo O'Neill's Saint Lucy is the only four-year-old lining up and receives plenty of weight from her elders.