Edinburgh coach Alan Solomons has recalled a host of big names as his side hope to clinch their place in the European Challenge Cup quarter-finals.
The Gunners travel to France to take on Pool 5 leaders Grenoble on Saturday targeting the victory that would see them overtake the Top 14 outfit to go through as group winners.
Defeat, however, would leave them vulnerable to an early exit, with only the three best runners-up qualifying for the last eight.
To protect against that, Solomons has called in a host of Scotland internationals, with centre Matt Scott, scrum-half Sam Hidalgo-Clyne, flanker John Hardie and front-rowers Alasdair Dickinson, Ross Ford and WP Nel all starting.
The head coach said: "We need to win this game to progress. We know it's going to be tough, they're a good side and they're at home.
"There are some real threats in their squad, they have a lot of experience and we're expecting a side that will really bring it to us in attack. Clearly we need to perform well on the day to get a result."