Blair back for Edinburgh
Mike Blair returns for Edinburgh as one of six changes to the team for the Magners League clash with the Ospreys.
The scrum-half, who captained Scotland against New Zealand last month before suffering concussion, will be partnered at half-back by his brother David Blair, who will be making his 50th Edinburgh appearance.
Prop Kyle Traynor will also make his 50th Edinburgh appearance, as will centre John Houston if he comes off the bench, while David Bishop is set to make his first start for the club against his former team.
Bishop, who joined Edinburgh on a three-month contract in October, spent three seasons with the Swansea-based side in the early part of his career.
Head coach Rob Moffat has congratulated the quartet on their respective achievements and called for a more complete performance than in the 24-19 win over Connacht last weekend.
Moffat said: "We were pleased to win the game last week, but we didn't play anywhere near as well as we know we can.
"We know we'll need to be better in a number of areas to beat the reigning champions away from home, but I'm confident we've got it in us to achieve a big result like that."
The remaining changes see Geoff Cross come in at prop, Esteban Lozada at second row and Ross Rennie into the back row.
Scotland internationals Allan Jacobsen and Ross Ford have been named on the bench as front-row replacements.