Edinburgh head coach Michael Bradley has made 13 changes for Friday's RaboDirect PRO12 clash with Ulster at Murrayfield.
Phil Godman is set to start at fly-half and Stuart McInally shifts from number eight to blindside flanker in the only players retained following the 17-12 derby loss to Glasgow last weekend.
Chris Paterson returns at full-back, with Tim Visser and Tom Brown named on the wings and Nick De Luca and James King at centre.
Captain Greig Laidlaw is set to start at scrum-half, behind a pack featuring the all-Scotland international front row of Allan Jacobsen, Ross Ford and Geoff Cross.
Esteban Lozada and Sean Cox are to start in the second row, with Roddy Grant and Netani Talei joining McInally in the back row.
Bradley said: "Like us, Ulster have so far enjoyed a successful Heineken Cup campaign but have not been as convincing in the RaboDirect PRO12, though they clearly took a big step towards addressing that last weekend against Munster (beating the defending champions 33-17).
"We have shown good form in front of our home support, winning six of our last seven at Murrayfield.
"However, Ulster have lost just one in their last five so will arrive with a lot of confidence, something which we will need to tackle early on.
"This is a huge match for us as a big month for the club continues and, while we've acknowledged the long-term importance of our January fixtures, the players and coaches focused fully on the size of the job at hand.
"Success would clearly give us the winning momentum we desire going into the Heineken Cup however that itself is not the objective. First and foremost this is about winning in the RaboDirect PRO12."