Injury-hit Rainey are intent on derby joy at struggling Quins
Top billing goes to the Division 2B Ulster derby between Belfast Harlequins and Rainey Old Boys with much at stake as both occupy different ends of the table.
Third-placed Rainey will fancy their chances at Deramore but they do travel to south Belfast without several of their key players. Tim Barker remains side-lined, while Michael McCusker is also out with injury and Charlie Clarke is suspended. Flanker Paul Pritchard is also carrying a knock but might play.
For Quins, who won at Skerries in the previous round, every game is vital as they aim to wriggle free of the relegation zone.
Also in 2B, Dungannon are at home to Wanderers with the hosts badly needing points to move away from ninth spot.
Bangor play Seapoint at Upritchard Park in what looks to be a must-win for the home side's play-off aspirations never mind keeping out of being dragged into the relegation mire.
The seasiders are in sixth, while their opponents are languishing in 10th, though they did beat Omagh last time out.
It's fourth versus third when Omagh take on Bruff at Thomas Mellon Playing Fields, where coach Phil Marshall's squad will be eager to get back to winning ways after losing last time out at Seapoint.
Seventh-placed City of Derry are at Thomond for a relegation-battling clash and are hoping to bring some of the doggedness they showed when beating Midleton by a point at Judges Road.
In 2A, Queen's University, who are sixth, play Navan at the Dub.
2A: Queen's University v Navan
2B: Belfast Harlequins v Rainey Old Boys, Dungannon v Wanderers
2c: Omagh Accies v Bruff, Thomond v City of Derry, Bangor v Seapoint