Rainey are determined to take a major stride in promotion quest
Rainey Old Boys can take a significant step towards securing third position when they host Sligo, who are a place below them.
Rugby round up Newsletter
Even though the Magherafelt club are already seven points ahead of their Connacht visitors, a positive result is still very much the requirement to keep Sligo at bay and build a more sizeable buffer between fourth and third.
Rainey, who won at Belfast Harlequins last Saturday, are still missing key players and, this week, Damian McMurray is unavailable so Conor Fitzsimons comes in while George Fritz is benched due to a groin strain.
Charlie Clarke is alongside Fritz as he returns from suspension.
Also in 2B, ninth-placed Quins are at Greystones while Dungannon, who won last weekend, visit leaders Barnhall which looks a daunting task as the Leinster side have won all 12 games so far.
In 2C, Bangor have lost their last five games and the sixth-placed side are at Bruff who are three places above them.
But for picking up bonus points they would be in much deeper trouble in the table, though they still badly need to gather some wins to clinch their safety.
Adam Alexander and Ali Lockhart miss out on the trip.
Omagh, in fourth, are on the road at Tullamore with Phil Marshall's squad keen to push on towards getting closer to securing a play-off spot.
City of Derry entertain Malahide with a third successive win on their mind.
In 2A, Queen's University play UL Bohemians at the Dub.
2A: Queen's University v UL Bohemians
2B: Rainey OB v Sligo, Greystones v Belfast Harlequins, MU Barnhall v Dungannon
2C: Bruff v Bangor, Tullamore v Omagh Accies, City of Derry v Malahide