Sale make Warriors suffer
Worcester suffered a 15th consecutive Aviva Premiership defeat and can surely now kiss goodbye to any lingering survival hopes.
This was a game the home side needed to win to give them hope of avoiding the drop, but for the fifth time this season Sale defeated them.
With their latest setback, Worcester remain 11 points behind Newcastle, who have a game in hand, and with only seven games remaining the mountain in front of them looks too high to scale.
Worcester could not recover from giving the opposition an early 11- point start, shaped by a Mark Cueto try and two penalties from Danny Cipriani.
The Warriors battled hard for the remainder of the half before falling away to concede a second-half try to Dan Braid, which was converted by Cipriani. The outside-half also added a penalty as did replacement Nick Macleod.
Worcester captain Chris Pennell missed two kickable penalties in the first half which would have provided a much needed boost as they failed to capitalise on their dominant second quarter. They had all the play but lacked the confidence and creativity to cross the visitors' line and their failure to do so saw heads drop.
The despondency resulted in a lethargic third-quarter performance and Worcester's only rewards were two late consolation tries from Mariano Galarza.
Cueto made his 200th Premiership appearance for Sale, who recalled full-back Tom Arscott and Jonathan Mills to their line-up. They replaced Rob Miller and Andrei Ostrikov, who were both rested.
Worcester were without their captain, Jonathan Thomas, who was suspended after being sent off in last week's game at Northampton.
He was replaced by Mike Williams with James Percival introduced at lock in place of Dean Schofield. John Andress was a late withdrawal so Euan Murray came in at prop.
Worcester started badly, conceding a penalty at the first ruck that enabled Cipriani to kick his side into an early lead.
Worse was to follow for the hosts as Sale extended that lead with a brilliant try. From inside his own half, David Seymour burst through the home defence. Then former Warrior Sam Tuitupou and Eifion Lewis-Roberts both made telling contributions to create a simple try for Cueto, who was able to celebrate his milestone in style.
Cipriani missed the conversion but sent over a penalty from halfway and with 13 minutes gone, Worcester were already up against it.
A half break from Jonny Arr was Worcester's first sign of attacking intent and they should have got on the scoreboard but skipper Pennell missed with two penalty attempts, which his side could ill-afford.
Pennell was given two further opportunities but declined to kick for goal in favour of attacking line-outs and Sale's defence held firm.
Sale suffered a blow when Dwayne Peel left the field with a leg injury to be replaced by Will Cliff as Worcester totally dominated the second quarter.
However they could not make the superiority count and Sale remained 11-0 in front at the interval.
Worcester brought on Ryan Lamb at half-time to make his debut but it was an inauspicious start for the outside-half as he booted his first touch straight over the in-goal area.
The error immediately surrendered the impetus to Sale who went further ahead when Cipriani kicked a simple penalty. Cipriani had another opportunity to kick a penalty but Sale chose a more attacking option as they realised the game was theirs.
Sale were rewarded when skipper Braid finished off a forward drive for the try which Cipriani converted, and the game was up for Worcester.
With 15 minutes to go, Worcester got on the score sheet when Galarza crashed over for a try. Macleod responded with a penalty before a further effort from Galarza converted by Lamb gave Warriors some respectability.