Les Kiss has rung the changes again as he makes nine alterations to his side to take on Glasgow in Scotstoun.
Jared Payne will make his first appearance of the campaign as the naturalised Kiwi comes straight in at full-back.
The Irish international has yet to feature this season after spending his summer on tour to South Africa while also dealing with a calf niggle. His restoration to the 15 jersey means fellow New Zealander Charles Piutau switches to the wing with Louis Ludik rounding out the back-three.
Payne will not be the only returning Test star to the panel with Rory Best named on the bench and figuring to come on as a replacement for captain Rob Herring at some stage in proceedings for his own seasonal bow.
A broken nose has not been enough for Stuart McCloskey to surrender his hold on the number 12 jersey and he is joined in the midfield by Darren Cave with Stuart Olding held in reserve.
Paddy Jackson and Ruan Pienaar start together at half-back for the second week in succession.
Up front, Andy Warwick gets the nod in the loosehead jersey. Callum Black will be on the bench with Kyle McCall outside the 23 having picked up an abdominal injury in training.
Alongside Warwick and Herring, summer signing Rodney Ah You will again pack down at tight-head.
Ross Kane has retained his place on the bench as Ah You's deputy despite the arrival of Georgian international Anton Peikrishvili on a short-term deal until mid-December.
Lock Franco van der Merwe had a rare break against Scarlets, coming off the bench in the second-half, but is restored to Ulster's engine room this evening alongside Alan O'Connor.
After banking 40 minutes of game time as a half-time substitute seven days ago Iain Henderson will be in from the start this time around and starts at blindside flanker.
Roger Wilson returns to the number 8 jersey with recent Irish cap Sean Reidy getting the nod again at openside.
Paul Marshall provides scrum-half cover off the bench with Pete Browne and Clive Ross the re-inforcements for the back five of the forward unit.