Wade and Kvesic to start for England
Wasps wing Christian Wade and Gloucester-bound flanker Matt Kvesic will make their England debuts in Saturday's first Test against Argentina in Salta.
England coach Stuart Lancaster has named three more uncapped players on the bench in the shape of Bath playmaker Kyle Eastmond, Sale prop Henry Thomas and new Saracens recruit Billy Vunipola.
Joe Marler will start at loosehead prop in a late change to England's plans after Alex Corbisiero was called up by the British and Irish Lions. The visitors anticipate a ferocious forwards contest and Kvesic's ability to win turnovers and disrupt the breakdown earned him the openside flanker role ahead of Tom Johnson.
"Matt Kvesic's inclusion was a difficult decision in that Tom Johnson has played well and has got experience. He has played well for me at openside and in South Africa," Lancaster said.
"I think Matt has got potential for the future and I think he has shown in the Barbarians game in particular but also in his form for Worcester that he can be effective in an offensive breakdown - so retaining possession, generating quick ball - and in defensive breakdowns where he can turn over ball and slow ball up."
Wade's selection on the right wing was more straightforward at the end of a season in which he scored 18 tries in 26 appearances for Wasps, and was named both players' player and young player of the year.
Wade takes over from Chris Ashton and Kvesic from Chris Robshaw, with the challenge of producing performances that will put pressure on the rested senior players ahead of the autumn international series.
"This is a big challenge but also a fantastic opportunity. It is the perfect challenge we want for this group of players - it will be Test-match rugby," added Lancaster. "The intensity will be higher than some of the players have played in before. The speed of thought and deed, dealing with the passion and emotion of it all will be critical. It was a difficult selection to get the balance right."
England team: M Brown (Harlequins); C Wade (Wasps), J Joseph (London Irish), B Twelvetrees (Gloucester), D Strettle (Saracens); F Burns (Gloucester), L Dickson (Northampton); J Marler (Harlequins), R Webber (Bath), D Wilson (Bath), J Launchbury (Wasps), D Attwood (Bath), T Wood (Northampton, capt), M Kvesic (Worcester), B Morgan (Gloucester).
Replacements: D Paice (London Irish), H Thomas (Sale Sharks), P Doran-Jones (Northampton), C Lawes (Northampton), B Vunipola (Wasps), R Wigglesworth (Saracens), K Eastmond (Bath), B Foden (Northampton).