Ulster utility back Will Addison looks set to jet out to Japan and join the Ireland squad ahead of the start of the World Cup after centre Robbie Henshaw suffered a hamstring injury.
While the extent of Henshaw's injury is not yet known, it was significant that Addison was withdrawn from Ulster's friendly against Glasgow Warriors despite being named in the starting line-up.
It is believed that Henshaw's ailment is enough to put his entire tournament at risk and would represent a significant blow to Ireland's hopes of lifting the Webb Ellis Trophy.
The Leinster centre was likely to wear the No.12 jersey alongside Bundee Aki in the opening game against Scotland, however reports from Japan say he is certain to miss that game and likely plenty more.
It is a cruel blow for Henshaw, who also missed the opening game of the 2015 World Cup through injury.
There is a silver lining for Addison, however, as he looks to be the benefactor, with the English-born utility back the one who would take the vacant spot in the squad.
Former Sale skipper Addison had an excellent, but injury impacted, debut season for Ulster and he was unfortunate not to be selected in the initial 31-man squad given the versatility he possesses.
Ireland head coach Joe Schmidt is likely to give an update on Henshaw's availability when he addresses the media on Sunday morning from the team's base in Chiba.